SENTÉ Bio Complete Serum



SENTÉ Bio Complete Serum is a lightweight nighttime formula that combines the benefits of patented HSA (Heparan Sulfate Analog) technology with sustained release retinoids and other key ingredients for the appearance of firmer and smoother skin with minimal irritation. Improves the appearance of fine lines and wrinkles and is recommended for all skin types with signs of solar and environmental damage.

  • Slow-release retinoids combine with Vitamin A and HSA to boost cell turnover without irritation, stimulating collagen and elastin production, and clinically shown to deliver more even skin tone within 8 weeks.
  • Ideal for sensitive skin and first-time retinol users
  • Hydrating formula helps reduce dryness and redness
  • Doesn't clog pores
  • Hypoallergenic
  • Dermatologist-tested
  • Paraben, gluten, and cruelty free


Ideal For: All skin types

Size: 1.0 oz / 30 mL

How to Use

After cleansing, apply 1-2 pumps onto face and rub gently. Allow the serum to absorb fully into skin before moving on to the next step of your routine. Follow up with a moisturizer, such as the SENTÉ Dermal Repair Cream, to soothe and lock in hydration.

Key Ingredients

  • Heparan Sulfate Analog: A patented repairing molecule that boosts the skin's immune response to inflammation and promotes repair from within
  • Retinol & Retinyl Safflowerate: Two retinoid forms to promote skin cell turnover for smoother, more even-looking skin tone
  • Unique Peptide Blend: Helps promote the synthesis of collagen without irritation

All Ingredients 

Aqua/Water/Eau, Butylene Glycol, Dipropylene Glycol, Cyclopentasiloxane, PEG-12 Dimethicone Crosspolymer, Dimethicone Crosspolymer, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethiconol, Dimethicone, Laureth-23, Laureth-4, Glycerin, Heparan Sulfate, Pentylene Glycol, Retinyl Safflowerate, Retinol, Lysophosphatidic Acid, Myristoyl Nonapeptide-3, Myristoyl Pentapeptide-17, Ethyl Safflowerate, Ethyl Flaxseedate, Dipalmitoyl Hydroxyproline, Allantoin, Panthenol, Hyaluronic Acid, Sodium Ascorbyl Phosphate, Polysorbate 80, Polyaminopropyl Biguanide, Fragrance/Parfum, Tromethamine.

Customer Reviews

Based on 4 reviews
agnija troyan
Not best

Unfortunately didn’t see any changes with my skin


This is a nice gentle retinol with plenty of hydration. The only con is that it's very silicone based so it's really greasy feeling and it does have fragrance. I think there are better retinols out there, but this is a decent option for a very gentle version if you like the texture.

So gentle and moisturizing!

I tried tretinoin and it destroyed my skin, making it ultra sensitive. I dumped that and went to this instead. I love the translucent oily gel texture of this that never irritates my skin and leaves it feeling moisturized. I love how it is gentle, yet effective. Absolutely perfect!!

Kayli West
Serum heaven

I got this as a sample. I was impressed and I am considering buying once my ISclinical serums run low!

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