SENTÉ Dermal Repair Cream



SENTE Skincare's first flagship product, Dermal Repair Cream, is the first clinically tested product containing Sente's patented HSA (Heparan Sulfate Analog) technology. It is solely the product that put Sente Skincare on the map as one of the top medical-grade skincare brands.

Why does this product have such a cult following? Well simply, because it is one of the best all -around moisturizing products on the market. This formulation hydrates the skin by attracting and retaining water, while simultaneously preserving skin fibers like collagen and elastin. In addition, it works to reduce redness and aid in wound healing. activates collagen production, and aids in skin cell communication and repair, among many other important functions.

  • Improves overall skin appearance
  • Improves skin tone, texture and firmness
  • Diminishes the appearance of fine lines and wrinkles
  • Hydrates and protects the skin barrier
  • Reduces redness and aids in skin healing
  • Repairs damaged skin
  • Gives and preserves the "bounce" or plumpness of skin


Ideal For: All skin types

Size: 1.7 fl oz / 50 mL

How to Use

After cleansing, apply 1-2 pumps onto fingertips and gently rub onto face. Allow the repair cream to fully absorb into the skin before moving on to the next step of your routine. Use twice daily once in the morning and again at night. 

Key Ingredients

  • Heparan Sulfate Analog: A patented repairing molecule that boosts the skin's immune response to inflammation and promotes repair from within
  • Vitamin E: A moisture replenishing antioxidant that protects skin from environmental pressures
  • Green Tea Extract: A soothing antioxidant that helps neutralize free radicals that cause inflammation and damage

All Ingredients 

Aqua/Water/Eau, Caprylic/Capric Triglyceride, C12-15 Alkyl Benzoate, Glycerin, Cetearyl Alcohol, Argania Spinosa Kernel Oil, Heparan Sulfate, Acetyl Glucosamine, Ethylhexyl Palmitate, Glyceryl Stearate, PEG-100 Stearate, Potassium Cetyl Phosphate, Cyclopentasiloxane, Dimethicone, Butylene Glycol, Tocopheryl Acetate, Tocopherol, Sodium Hyaluronate, Camellia Sinensis Leaf Extract, Chenopodium Quinoa Seed Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Aminomethyl Propanol, Sodium Benzoate, Sorbic Acid, Potassium Sorbate, 1,2-Hexanediol, Caprylyl Glycol, Phenoxyethanol, Disodium EDTA.

Customer Reviews

Based on 21 reviews
Oksana B
Will repurchase

Fantastic cream. I have combo skin and this cream balances it out very nicely. I normally get oily throughout the day with other creams and have to blot multiple times. Not with Sente. The skin is left smooth and soft. No adverse reactions, soothes irritation and redness nicely. I use it as both night and day time moisturizer

Holy Grail Moisturizer

I have roascea and I am acne prone skin and this moisturizer always impresses with it’s ability for my skin to tolerate Vitamin C and retinol together and strengthens my barrier to prevent inflammation and sensitivity

Great Moisturizer

I was hesitant to use this moisturizer as I have oily acne prone skin. It has an ingredient that potentially can block pores. However I have found it is lightweight and so soothing to my inflammation. It helps reduce the inflammation and calm the skin. It has not clogged my pores.

Great AM moisturizer under sunscreen

When I first tried the Dermal Repair cream, I was a bit disappointed because it was definitely not enough for my dry skin at night. It's very lightweight and my skin loses water easily and no amount of this was enough to keep it moisturized at night. However!!! It turned out to be a great moisturizer under my sunscreen and works really well with layering It's hydrating and emollient enough that I still get a good amount of playtime with this on the skin, which makes it easy to spread. I don't have any pilling with this either. The biggest thing that I wish Senté would differentiate in their marketing is that their products really only work for redness that's related to inflammation- if your redness is vascular rather than inflammatory, go get that ish lasered at the dermatologist.

Liz Daicos
Perfect moisturizer

I’ve repurchased this cream many times now. It’s an unassuming light weight moisturizer but amazes me every time I put it on because it nourishes completely. It immediately calms down any rosacea redness and soaks right in. It even calmed down a sore red nose from a cold I had. It’s perfect for day and night because it leaves no greasy residue and it also layers perfectly. In the winter if my skin is extra dry I sometimes layer a sleeping mask over top to further lock it in. Only downside is the price.