Formulated with the most advanced Growth Factor technology (TNS-MR), SkinMedica TNS Advanced Serum supports rapid, comprehensive skin rejuvenation with significant, visible improvements in coarse wrinkles, fine lines and overall texture. With continued use, TNS Advanced Serum lifts the appearance of sagging skin and enhances firmness to reclaim smooth, tight and youthful-looking skin that appears up to 6 years younger after 12 weeks. 

Researchers at SkinMedica created a new, proprietary blend of 450 growth factors that delivers results twice as fast: Instead of it taking 30 days to start working - opposed to the original- you'll see smoother skin in two weeks, and you won't have to put up with any obvious odor (a new manufacturing process does away with growth factors' scent). The updated SkinMedica TNS Advanced Serum also includes a broader range of ingredients — peptides, algae, and probiotic ferments, along with the growth factors — to deliver a wider spectrum of results, says cosmetic chemist Ginger King.

In addition to smoothing lines and improving skin texture, it also helps fade dark spots and firms sagging skin, even along the jawline, which is a really tall order for skin care. "These results — and how fast the serum delivers them — are innovative, and a clinical study includes skin biopsies to prove that it's treating multiple skin issues, says Doris Day, a dermatologist and clinical associate professor of dermatology at NYU Langone in New York City. The study showed improvement in skin texture after 14 days of twice-daily use and significant improvement in sagging and overall photo damage after eight weeks, including a 22 percent reduction in fine lines and wrinkles and a 15 percent reduction in rough skin.